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Singh, Anil Kumar

Biocompatibility Studies of Electron Beam Cured Pressure Sensitive Adhesive Tape for Medical Application

Abstract Views :292 | PDF Views:103

Authors

Anil Kumar Singh ¹, Gurdeep Singh ²

Affiliations
1 Shriram Institute for Industrial Research, 19-University Road, Delhi 110 007, IN
2 Vinoba Bhave University, Hazaribag, Jharkhand 825 301, IN

Source

Current Science, Vol 110, No 6 (2016), Pagination: 1023-1030

Abstract

Polyurethane (PU)-based pressure-sensitive adhesive (PSA) tapes are commonly used during surgery. Such devices made for biomedical applications must be biocompatible and biologically safe while in use in the human body as their ingredients may leach off of a device into an adjacent tissue and can harm the body during or after application. In the present study, various methods required for biocompatibility establishment, e.g. cytotoxicity, irritation and sensitization for a device, have been analysed and presented following suitable specifications. The study also emphasizes on the developmental and curing mechanism of biomedical adhesive tape by electron beam (e-beam) irradiation.

Full Text

References

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Singh, A. K., Mehra, D. S., Niyogi, U. K., Sabharwal S. and Khandal, R. K., Polyurethane based pressure sensitive adhesives (PSAs) using e-beam irradiation for medical application. J. Polym.Material., 2011, 28(4), 525–542.

Singh, A. K., Mehra, D. S., Niyogi, U. K., Sabharwal, S. and Khandal, R. K., Effect of tackifier and crosslinkers on electron beam curable polyurethane pressure sensitive adhesive. Radiat.Phys. Chem., 2012, 81(5), 547–552.

Singh, A. K., Mehra, D. S., Niyogi, U. K., Sabharwal, S., Swiderska, J., Czech, Z. and Khandal, R. K., Effect of crosslinkers on adhesion properties of electron beam curable polyurethane pressure sensitive adhesive. Int. J. Adhes. Adhes., 2013, 41, 73– 79.

Singh, A. K., Niyogi, U. K., Sabharwal, S., Kowalczyk, A., Czech, Z. and Mehra, D. S., Shrinkage studies in electron beam curable polyurethane pressure sensitive adhesive. J. Adhes. Sci. Technol., 2013, 27(14), 1511–1524.

Singh, A. K., Mehra, D. S., Niyogi, U. K., Sabharwal, S. and Singh, G., Breathability studies of electron beam curable polyurethane pressure sensitive adhesive for bio-medical application.Radiat. Phys. Chem., 2014, 103, 75-83.

Singh, A. K., Mehra, D. S., Niyogi, U. K., Sabharwal, S. and Singh, G., Life performance evaluation of electron beam-curable polyurethane pressure-sensitive adhesive tape for medical applications.J. Adhes. Sci. Technol., 2014, 28(12), 1192–1206.

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Viable Feedstock Options and Technological Challenges for Ethanol Production in India

Abstract Views :264 | PDF Views:82

Authors

Anil Kumar Singh ¹, Neelima Garg ¹, Ajay Kumar Tyagi ¹

Affiliations
1 Shriram Institute for Industrial Research, 19, University Road, Delhi 110 007, IN

Source

Current Science, Vol 111, No 5 (2016), Pagination: 815-822

Abstract

Though improvements in processing and technology are important, the fluctuating price of inputs such as molasses, corn, sugar beet, sugarcane, sweet sorghum, starch, etc. and their seasonal availability play an important role in ethanol industry. As a matter of fact, the ethanol industry based on conventional resources has reached its saturation point. Technologies for ethanol production from lignocellulosics are being developed by scientists world over with the objective of exploiting the potential of a resource, which is otherwise considered a waste, to generate energy. The focus has been to produce ethanol in a cost-effective manner, besides aiming to find use of its by-products as food supplements for cattles, etc. Recent developments like adoption of technologies such as dry grind fractionation, which is now commercially viable, would reduce the cost of milling; wet milling being cost-intensive and dry milling requiring smaller plants.

Keywords

Ethanol, Feedstock, Lignocellulosics, Molasses, Sugarcane.

Full Text

Soil Organic Carbon Stock in Agroforestry Systems in Western and Southern Plateau and Hill Regions of India

Abstract Views :278 | PDF Views:94

Authors

Ram Newaj ¹, O. P. Chaturvedi ¹, Dhiraj Kumar ¹, Rajendra Prasad ¹, R. H. Rizvi ¹, Badre Alam ¹, A. K. Handa ¹, S. B. Chavan ¹, Anil Kumar Singh ¹, Mayank Chaturvedi ¹, P. S. Karmakar ¹, Abhishek Maurya ¹, Abhishek Saxena ¹, Gargi Gupta ¹, Kedari Singh ¹

Affiliations
1 ICAR-Central Agroforestry Research Institute, Jhansi 284 003, IN

Source

Current Science, Vol 112, No 11 (2017), Pagination: 2191-2193

Abstract

The rising level of carbon dioxide (CO₂) in the atmosphere is a major concern, as scientific evidences show that it is the primary cause of global warming. CO₂ concentration is expected to double by the middle or end of the 21st century, with a temperature rise between 1.5°C and 4.5°C (ref. 1). The importance of agroforestry as a land-use system is receiving wider recognition not only in terms of agricultural sustainability, but also in issues related to carbon sequestration or climate change.

Full Text

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Controlled Hydrolytic Degradation of Polyglycolide–Caprolactone-Based Bioabsorbable Copolymer

Abstract Views :229 | PDF Views:75

Authors

Anil Kumar Singh ¹, Rakesh Kumar Singh ¹, Ajay Kumar Tyagi ¹

Affiliations
1 Material Science Division, Shriram Institute for Industrial Research, 19-University Road, Delhi 110 007, IN

Source

Current Science, Vol 113, No 07 (2017), Pagination: 1354-1360

Abstract

Polyglycolide–caprolactone (PGCL)-based copolymer was synthesized from glycolide and caprolactone by ring opening polymerization in the presence of stannous octoate catalyst and diethylene glycol initiator. The effects of prepolymerization time, monomer ratio, monomer-to-catalyst and monomer-to-initiator ratios on per cent weight conversion were optimized. The end-capped copolymer was synthesized to make absorbable sutures having controlled bioabsorbability at different pH levels. It was observed that endcapped absorbable copolymer was more stable at pH 10.0 compared to uncapped absorbable material. End-capped copolymer also retained higher tensile strength compared to uncapped copolymer after 21 days. This phenomenon of controlled hydrolytic degradation of PGCL-based bioabsorbable polymer having terminal group end-capping can be attributed to less availability of hydrophilic end groups facilitating hydrolytic degradation of polymers.

Keywords

Biocompatibility, Bioabsorbable Copolymer, Hydrolytic Degradation, Polyglycolide–Caprolactone, Suture.

Full Text

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